Location:
Paul & Mildred Berg Hall, Li Ka Shing Center, Stanford
and virtual option
Day 1 Event Recordings
Day 2 Event Recordings
Photo credits: Siyeon Rhee, PhD
View the Agenda
Welcome to 2024 Stanford Drug Discovery Symposium. This symposium provides a valuable and important platform for inspiring interdisciplinary exchange at the forefront of drug research and will support a fantastic networking experience. It provides a great resource for researchers, pharmaceutical companies, investment groups, and those in the wider biomedical community interested in discovering new drugs and improving patient care. We look forward to an exciting two days of talks and discussion.
— Joseph C. Wu, MD, PhD | Director, Cardiovascular Institute
Participants
George Addona, PhD
Senior VP and Head of Discovery, Preclinical Development, and Translational Medicine, Merck
Carolyn Bertozzi, PhD
Baker Family Director of Stanford ChEM-H, Anne T. and Robert M. Bass Professor, Stanford University
Rob Califf, MD
Commissioner, U.S. Food and Drug Administration
Don Cleveland, PhD
Department Chair and Professor, Cellular and Molecular Medicine, University of California San Diego
Paulo Fontoura, MD, PhD
Global Head and SVP of Neuroscience, Immunology, Ophthalmology, and Rare Diseases, Roche
Karin Immergluck, PhD
Director, Stanford Office of Technology and Licensing
Michelle Longmire, MD
Chief Executive Officer, Co-Founder, Medable
Fady Malik, MD, PhD
Executive Vice President of Research & Development, Cytokinetics
Flavius Martin, MD
Executive Vice President of Research, Gilead Sciences
Yevgeniya Nusinovich, MD, PhD
Science Editor, Science Magazine
Camille Samuels, MBA
Partner, Venrock
Daniel Skovronsky, MD, PhD
CSO and Pres., Lilly Research Labs; Pres., Immunology, Eli Lilly and Company
Gregory Verdine, PhD
Erving Professor of Chemistry, Harvard University
Sharon Barr, PhD
Executive Vice President, BioPharmaceuticals R&D, AstraZeneca
Paul Biondi, MBA
Executive Partner and President of Pioneering Medicine, Flagship Pioneering
Rosa Canet-Avilés, PhD
Vice President, Scientific Programs & Education,California Institute for Regenerative Medicine
Marianne De Backer, MSc, PhD, MBA
Chief Executive Officer and Director, Vir Biotechnology
Julie Grant, MBA, MPhil
General Partner, Canaan Partners
Joe Jimenez, MBA
Co-Founder and Managing Director, Aditum Bio
Thomas Lynch, MD
President and Director, FredHutchinson Cancer Center
Mathai Mammen, MD, PhD
Chief Executive Officer, President, and Chairman, FogPharma
Lloyd Minor, MD
Carl and Elizabeth Naumann Professorship for the Dean, Stanford School of Medicine
Robert Plenge, MD, PhD
Executive Vice President, Chief Research Officer, Head of Research, Bristol Myers Squibb
Wade Shen
Director of Proactive Health Office, Advanced Research Projects Agency for Health
Andrew Trister, MD, PhD
Chief Medical Officer and Chief Scientific Officer, Verily Life Sciences
Michelle Williams, ScD
Joan and Julius Jacobson Professor of Epidemiology and Public Health,Harvard T.H. Chan School of Public Health
Hal Barron, MD
Chief Executive Officer and Founder, Altos Labs
Paul Burton, MD, PhD
Senior Vice President and Chief Medical Officer, Amgen
Patrizia Cavazzoni, MD
Director, Center for Drug Evaluation and Research, Food and Drug Administration
Michael Devoy, MD
CMO and EVP of Medical Affairs and Pharmacovigilance for the Pharmaceuticals Division, Bayer
Aida Habtezion, MD
Chief Medical Officer and Head of Worldwide Medical and Safety, Pfizer
Hallie Kuhn, PhD
Senior Vice President, Alexandria Venture Investments
Grace Han McMahon
Associate Vice President, Pacific Business Development & Licensing, Merck
Peter Marks, MD, PhD
Director, Center for Biologics Evaluation and Research, Food and Drug Administration
Deep Nishar, MBA
Managing Director, General Catalyst
Joni Rutter, PhD
Director, National Center for Advancing Translational Sciences, National Institutes of Health
Abhishek Shukla
Managing Director, Prosperity7 Ventures
Andrea van Elsas, PhD
Partner, Third Rock Ventures
Bei Zhang, PhD
Corporate Vice President & TA Head, Diabetes, Obesity, & MASH (DO&M), Global Drug Discovery, Novo Nordisk
Lifetime Achievement Awardees
Catherine Boileau, PhD, PharmD
Emeritus Professor of Genetics, Medical School of Paris Cité University, Inserm UMR1148 LVTS Research Center, Bichat University Hospital
Helen Hobbs, MD
Philip O'Bryan Montgomery Jr., MD, Distinguished Chair in Developmental Biology
Eugene McDermott Distinguished Chair for the Study of Human Growth and Development
UT Southwestern Medical Center
All times listed are PT
8:30-9:00 am
Registration
Li Ka Shing Center, Paul & Mildred Berg Hall
291 Campus Drive, Stanford
9:00 am| Opening Remarks
Joseph Wu, MD, PhD
Director, Stanford Cardiovascular Institute; Simon H. Stertzer, MD, Professor of Medicine and Radiology, Stanford University School of Medicine
Lloyd Minor, MD
Carl and Elizabeth Naumann Professorship for the Dean, Stanford University School of Medicine
9:15-11:00 am | Session I: Drug Discovery I: Opportunities and Challenges
Moderators: Mathai Mammen, MD, PhD (Chief Executive Officer, President, and Chairman, FogPharma) and Sanjay Malhotra, PhD (Professor, Oregon Health & Science University)
Flavius Martin, MD
Executive Vice President of Research, GileadSciences
Research at Gilead: Success Through Synergy
Robert Plenge, MD, PhD
Executive Vice President, Chief Research Officer, Head of Research, Bristol Myers Squibb
Improving R&D Productivity for Cardiovascular Medicines
Michael Devoy, MD
Chief Medical Officer and Executive Vice President of Medical Affairs and Pharmacovigilance for the Pharmaceuticals Division, Bayer
Towards Precision Medicine Through Cell and Gene Therapy: Considerations for Discovery, Development, and Healthcare Implementation
Aida Habtezion, MD
Chief Medical Officer and Head of Worldwide Medical and Safety, Pfizer
AI and Machine Learning Across Pfizer’s Research and Development
Sharon Barr, PhD
Executive Vice President, BioPharmaceuticals R&D, AstraZeneca
Driving Patient Centric Drug Discovery
Panel Discussion
11:00-12:30pm
Networking Lunch
Alumni Lawn in front of Li Ka Shing Center
12:30-1:00 pm | Session II: Regulatory Insights: Fireside Chat with FDA Commissioner Califf
Moderator: Lloyd Minor, MD (Carl and Elizabeth Naumann Professorship for the Dean, Stanford University School of Medicine)
Robert Califf, MD
Commissioner, U.S. Food and Drug Administration
1:00-1:45 am | Session III: Big Opportunities and Pressing Issues in Drug Discovery: Conversation with Experts
Moderator: Hal Barron, MD, PhD (Chief Executive Officer and Founder, Altos Labs) and Kuldev Singh, MD (Professor, Stanford University School of Medicine)
Marianne De Backer, MSc, PhD, MBA
Chief Executive Officerand Director, Vir Biotechnology
Michelle Longmire, MD
Chief Executive Officer, Co-Founder, Medable
Daniel Skovronsky, MD, PhD
Chief Scientific Officer and President, Lilly Research Laboratories; President, Immunology, Eli Lilly and Company
Bei Zhang, PhD
Corporate Vice President & TA Head, Diabetes, Obesity, & MASH (DO&M), Global Drug Discovery, Novo Nordisk
Michelle Williams, ScD
Joan and Julius Jacobson Professor of Epidemiology and Public Health, Harvard T.H. Chan School of Public Health
1:45-2:10 pm
Coffee Break
2:10-2:55 pm | Session IV: Investing in Innovation: Navigating the Landscape of Drug Discovery Ventures
Moderators: Karin Immergluck, PhD (Director, Stanford Office of Technology and Licensing) and Kuldev Singh, MD (Professor, Stanford University School of Medicine)
Grace Han McMahon, JD, MBA
Associate Vice President and Head, Pacific Hub, Business Development & Licensing, Merck
Paul Biondi, MBA
Executive Partner and President of Pioneering Medicines, Flagship Pioneering
Andrea van Elsas, PhD
Partner, Third Rock Ventures
Joe Jimenez, MBA
Co-Founder and Managing Director, Aditum Bio
2:55-4:00 pm | Session V: Reflecting on Excellence: Presentation of Lifetime Achievement Award Lecture
Introduction:
Joseph Wu, MD, PhD
Director, Stanford Cardiovascular Institute; Simon H. Stertzer, MD, Professor of Medicine and Radiology, Stanford University School of Medicine
Awardee Lecture:
Catherine Boileau, PhD, PharmD
Emeritus Professor of Genetics, Medical School of Paris Cité University
Inserm UMR1148 LVTS Research Center, Bichat University Hospital
PCSK9: from Genetic Heterogeneity of Familial Hypercholesterolemia to Paradigm Shifts
Awardee Lecture:
Helen Hobbs, MD
Philip O’Bryan Montgomery Jr., MD, Distinguished Chair in Developmental Biology; Eugene McDermott Distinguished Chair for the Study of Human Growth and Development, UT Southwestern Medical Center
PCSK9: From Nature's Loss to Patient's Gain
Moderated Q&A Session
4:00-4:05 pm | Day 1 Summary
Joseph Wu, MD, PhD
Director, Stanford Cardiovascular Institute; Simon H. Stertzer, MD, Professor of Medicine and Radiology, Stanford University School of Medicine
4:05-5:00 pm
Wine and Cheese Networking Reception
Li Ka Shing Center, Paul & Mildred Berg Hall
6:15 pm
Stanford Drug Discovery Symposium Dinner for Speakers and Moderators
Hosted by Alexandria Real Estate Equities
All times listed are PT
8:30-9:00 am
Registration
Li Ka Shing Center, Paul & Mildred Berg Hall
291 Campus Drive, Stanford
9:00 am | Day 2 Welcome
Joseph Wu, MD, PhD
Director, Stanford Cardiovascular Institute; Simon H. Stertzer, MD, Professor of Medicine and Radiology, Stanford University School of Medicine
9:05-10:15 am | Session VI: Academia to Industry and Back
Moderators: Yevgeniya Nusinovich, MD, PhD (Senior Editor, Science) and Sanjay Malhotra, PhD (Professor, Oregon Health & Science University)
Don Cleveland, PhD
Department Chair, Cellular and Molecular Medicine (CMM); Professor, Cellular and Molecular Medicine, University of California San Diego
Designer DNA Drug Therapy for NeurodegenerativeDisease
Gregory Verdine, PhD
Erving Professor of Chemistry, HarvardUniversity
Toward Universal Druggability
Thomas Lynch, MD
President and Director,Fred Hutchinson Cancer Center
Drug Discovery at Fred Hutch Cancer Center
Panel Discussion
10:15-10:40 am
Coffee Break
10:40-11:25 pm | Session VII: Securing the Path Forward: Funding Opportunities in Drug Discovery
Moderators: Camille Samuels, MBA (Partner, Venrock) and Mark Mercola, PhD (Professor, Stanford University School of Medicine)
Abhishek Shukla, MBA
Manager Director, Prosperities7 Ventures
Julie Grant, MBA, MPhil
General Partner, Canaan Partners
Deep Nishar, MBA
Managing Director, General Catalyst
Hallie Kuhn, PhD
Senior Vice President, Alexandria Venture Investments
11:25-12:45
Networking Lunch
Alumni Lawn in front of Li Ka Shing Center
12:45-2:10 pm | Session VIII: Drug Discovery II: Core Principles and Frontiers
Moderators: Fady Malik, MD, PhD (Executive Vice President of Research and Development, Cytokinetics) and Mark Mercola, PhD (Professor, Stanford University School of Medicine)
George Addona, PhD
Senior Vice President and Head, Discovery, Preclinical Development, and Translational Medicine, MerckResearch Laboratories
Discovery of an Orally Bioavailable Macrocyclic PCSK9 Inhibitor
Paul Burton, MD, PhD
Senior Vice President and Chief Medical Officer, Amgen
Data & Patients: Novel Partners in Drug Development
Andrew Trister, MD, PhD
Chief Medical Officer and Chief Scientific Officer, Verily Life Sciences
Plaiting The Golden Braid: Incorporating Patient-Generated Data In Clinical Development
Paulo Fontoura, MD, PhD
Global Head andSenior Vice President of Neuroscience, Immunology, Ophthalmology, and Rare Diseases, Roche
Future Advances in the Treatment of Neuromuscular Disorders
Panel Discussion
2:10-2:35 pm
Coffee Break
2:35-4:15 pm | Session IX: Perspectives and Opportunities in Translational Research and Therapeutics
Moderators: Carolyn Bertozzi, PhD (Baker Family Director of Stanford ChEM-H, Anne T. and Robert M. Bass Professor, Stanford University), and Kuldev Singh, MD (Professor, Stanford University School of Medicine)
Peter Marks, MD, PhD
Director, Center for Biologics Evaluation and Research, Food and Drug Administration
Delivering on the Promise of Genetic Medicines
Patrizia Cavazzoni, MD
Director, Center for Drug Evaluation and Research, Food and Drug Administration
Advances and Innovations in CDER’s Approach to Drug Development
Rosa Canet-Avilés, PhD
Vice President, Scientific Programs & Education,California Institute for Regenerative Medicine
Update on CIRM Funding Programs
Joni Rutter, PhD
Director, National Center for Advancing Translational Sciences, National Institutes of Health
Translational Science: Maximizing the Success of Therapeutic Development
Wade Shen
Director of Proactive Health Office, Advanced Research Projects Agency for Health (ARPA-H)
AI and Drug Discovery @ ARPA-H
Panel Discussion
4:15 pm | Closing Remarks
Joseph Wu, MD, PhD
Director, Stanford Cardiovascular Institute; Simon H. Stertzer, MD, Professor of Medicine and Radiology, Stanford University School of Medicine
4:20-5:30
Networking and Poster Session
Event Program & Poster
FAQs
Paul & Mildred Berg Hall
Li Ka Shing Center, Stanford University
291 Campus Drive, Stanford, CA 94305
Please allow yourself plenty of time to find parking, as space is limited on Stanford campus. Please refer to the below information for resources on purchasing a parking permit and finding visitor parking.
- How to Purchase Visitor Parking
- Link to Searchable Campus Map(search for Li Ka Shing Center)
- Printable Map to Li Ka Shing Center
- ParkMobile Zone Numbers for Visitor Parking
- Suggested ParkMobile Zone Numbers – within walking distance address links:
- Stock Farm Lot (L-20) near Welch Rd. and Oak Rd.
- Zone number:7205
- Stock Farm Lot (L-17) near Welch Rd. at Campus Drive West
- Zone number:7217
- LKSC / Beckman Lot (L-15) – 3-hour maximum; one visit per day
- Zone number:7215
- Roth Way Garage at Campus Drive West between Quarry Rd. and Roth Way – 4-hour maximum parking; one visit per day
- Zone number:7201
- Searsville Lot (L-22)
- Zone number:7222
- Via Ortega Garage
- Zone number:7202
- Stock Farm Lot (L-20) near Welch Rd. and Oak Rd.
Due to the overwhelming response to SDDS 2024, we have reached full capacity for in-person attendance. We are not able to accommodate walk-in registration for the event. We encourage you to register for virtual attendance. The livestream will be available atstarting onMonday, April 29, at 9:00 am PT.
Due to the overwhelming response to SDDS 2024, we have reached full capacity for in-person attendance. We are no longer able to accommodate any waitlist ticket requests for the event.You must have a paid ticket to attend in-person. We encourage you to register for virtual attendance. The livestream will be available atstarting onMonday, April 29, at 9:00 am PT.
Please receive your badge after arriving at the Li Ka Shing Center (LKSC). Please pick-up your badge in the line corresponding to your last name. Please be prepared to show your purchased ticket for in-person attendance.
To use the University’s wireless network while on-campus, please use the Stanford Visitor network. How to get online:
1. Select “Stanford Visitor” from the list of wireless networks.
2. Open a browser and load any URL. You will then be directed to an access page. On a mobile phone, the access page should open automatically.
3. “Accept” to acknowledge the terms of use.
For your convenience, there is a lactation room available in the Li Ka Shing Center building. There is a lockable door from inside. The room has 2 chairs, side tables, and access to power. Please note that there is no sink or water, nor is there space for fridge storage. For access, please contact any program staff at the registration tables.
Foundation Sponsors
Platinum Sponsors
Gold Sponsors
Silver Sponsors
Media Partners
Interested in sponsoring SDDS 2024? Contact us today!
Organizers
Amanda Chase, PhD
Associate Director of Strategic Research Development
Stanford Cardiovascular Institute
Kuldev Singh, MD
Professor of Ophthalmology
Stanford University School of Medicine
Sanjay Malhotra, PhD
Professor, Cell, Developmental & Cancer Biology; Director, Center for Experimental Therapeutics
OHSU
Joseph Wu, MD, PhD
Director, Stanford CVI
Simon H. Stertzer, MD, Professor, Department of Medicine and Radiology
Stanford University School of Medicine
Mark Mercola, PhD
Professor of Medicine
Stanford University School of Medicine
Francesca Mae G. Tongco, MS-HCA
Project Coordinator
Stanford Cardiovascular Institute
For additional information, please contact Joseph C. Wu, MD, PhD, or Francesca Tongco.
